World Health Organization to resume hydroxychloroquine arm of Solidarity Trial

A major study of hydroxychloroquine for Covid-19 is drawing criticism—and a formal correction

Lancet journal says it's concerned about the validity of widely cited hydroxychloroquine study touted as a COVID-19 cure

Amongst those who received hydroxychloroquine, 49 developed the disease (or compatible symptoms such as fever or cough), compared with 58 in the group that received the placebo.

US President Donald Trump has touted hydroxychloroquine, saying he has taken it as a preventative against the coronavirus.

University of Minnesota researchers tested 821 people who had recently been exposed to the virus or lived in a high-risk household.

"While we had hope this drug would work in this context, our study demonstrates that hydroxychloroquine is no better than placebo when used as post-exposure prophylaxis within four days of exposure to someone infected with the new coronavirus", said Dr. Todd Lee of the MUHC, one of the study's lead authors.

The medical journal has issued an "expression of concern" over a large-scale study of hydroxychloroquine and chloroquine that led to the World Health Organization to pause clinical trials of the former as a potential treatment for COVID-19.

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Several trials of the drug have been stopped over concerns about its safety for treating COVID-19 patients raised by health regulators and previous less rigorous studies and.

But other critics, like Francois Balloux of University College London, raised concerns over the way the study was conducted even though they are sceptical the drugs themselves would work as a treatment for COVID-19.

As many as 3,100,711 people have recovered from Covid-19, which has spread to 213 countries and territories across the world.

However, the drug did not seem to cause serious harm, though - about 40% on it had side effects, mostly mild stomach problems.

It appears a major study published 22nd May in renowned global medical journal The Lancet, which ruled antimalarial drugs touted by Donald Trump as possible COVID-19 treatments could be lethal, was based on data supplied by an obscure analytics company, Surgisphere, which counts a sci-fi writer and exotic model among its staff.

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As of Wednesday, Bangladesh had confirmed 55,140 coronavirus cases with the death toll rising to 746 after 37 new fatalities were reported.

Results were no different among a subgroup of participants who were taking zinc or vitamin C, which some people believe might help make hydroxychloroquine more effective. "Benefit may be there", ICMR had said.

The Canadian research is co-ordinated with a large study by Dr. David Boulware at the University of Minnesota.

In March, Trump, with little scientific evidence, said hydroxychloroquine used in combination with the antibiotic azithromycin had "a real chance to be one of the biggest game changers in the history of medicine". Participants enrolled nationwide in the US and in Quebec, Manitoba and Alberta in Canada.

Officials say they found out the researchers excluded data on patients who didn't respond well to the treatment and that they did not clarify what they meant when they said patients were 'virologically cured'.

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